Bio Dome (1996)

Bud and Doyle are a pair of aimless slackers with no real direction in life. While their environmentally-conscious girlfriends are passionate about saving the planet, the two couldn't care less. One day, they accidentally stumble into a high-stakes scientific experiment—a year-long mission in a sealed "Bio-Dome" with no contact with the outside world—and unwittingly become part of the project.